Prevora has first-in-class approvals to prevent dental decay in high risk adults in Canada (DIN02046245), the United Kingdom (PL30669) and Ireland (PA1205). The European Medicines Agency has issued a positive opinion for Prevora (EMA/H/A-29/1258) as part its Mutual Recognition arbitration process. This EMA opinion is expected to facilitate a successful Mutual Recognition process to EU member states, at the request of CHX. CHX intends to trigger Mutual Recognition in certain member states upon establishing product distribution.

CHX is preparing a do-able, low-risk, high-impact Phase III clinical trials program for FDA approval, and for expanding Prevora’s therapeutic indication in Canada, the UK, Ireland and the EU. The focus of this clinical research is oral inflammation and systemic inflammation. This focus is based on (a) years of observation by Canadian dental professionals that Prevora patients experience rapid and long-lasting improvement in their periodontal health, and (b) growing scientific evidence that improved periodontal health is linked to lower systemic inflammation. Improved management of inflammation is an important goal of medical practitioners and third party payers. If and when approved for this use, Prevora will be a unique, topical approach to lowering inflammation.


“I have enjoyed better gums and teeth with Prevora – for years.”

- Nellie E.


“Prevora has improved my gums and protected my teeth. This is very important to me”.

- Judith G.


“I couldn’t brush my teeth for 6 weeks after surgery for oral cancer. But with Prevora treatment before my surgery, my teeth were fine".  

- Richard J.


“I am a stroke survivor and brushing my teeth is difficult. With Prevora over the past few years, my teeth are healthy and so are my gums.”

- Thomas B.


“After years of several fillings each year, Prevora has made me cavity free for 10 years.”

- Bruce B.


“No cavities for years. Painless. Affordable. What more do you need to know?”

- John P.


“Mom’s oral health has really improved with Prevora. This gives me peace of mind”.

- Lori T.

Daughter of Phyllis P.

For years I have had troubles with my teeth and gums. Since Prevora, it is the first time I feel like my teeth and gums are healthy.

Margaret C.


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